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Fetish. Your order is held for processing until we have received the cleared payment.Effects of dietary fish oil on microsomal cytochrome P450 in dietary-restricted rats.
We have previously shown that growth and final body weight of rats are not altered by the absence of dietary linoleic acid (18:2) and that levels of the intestinal isoenzyme of cytochrome P450 (P450) 1a are increased in dietary-restricted rats. Other investigators have shown that omega-3 fatty acids tend to replace dietary 18:2 in cell membranes and, as such, increase the activity of microsomal P450 1a. The possibility was therefore raised that the growth of dietary-restricted rats fed omega-3 fatty acids would be different than that of their omega-6 fatty acid-fed counterparts. We therefore compared the growth and liver isoenzyme 1a and intestinal P450 activity in dietary-restricted rats fed either fish oil or soybean oil. Rats were fed one of these two diets beginning at five weeks of age and continued on their respective diets until 14 or 15 weeks of age. The fish oil-fed rats were given 0.2% fish oil for 14 to 15 weeks. Dietary restriction decreased weight gain (final weight:g food intake) for both groups. Rats fed fish oil had higher hepatic and intestinal P450 activity than rats fed soybean oil. Growth was greater and final body weight was higher in rats fed fish oil. These data indicate that dietary omega-3 fatty acids generally replace dietary 18:

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Swoope-wake-up-album-zip

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