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He urges Barcelona and offers it an incentive to persuade Washington to release the names.Phase I/II dose-response and pharmacokinetic study of paclitaxel with biweekly docetaxel (Capecitabine) in patients with advanced breast and non-small cell lung cancer.
Paclitaxel is a new antimicrotubule agent that is effective in advanced breast and non-small cell lung cancer (NSCLC). Biweekly docetaxel is a novel taxoid that has shown superior pharmacokinetic and antitumor activity to a weekly schedule. We conducted a phase I/II study to evaluate the activity and toxicity of paclitaxel with biweekly docetaxel in a dose-escalation and schedule-finding setting. Patients with measurable breast cancer or NSCLC received escalating doses of paclitaxel on days 1 and 15, every 28 days, with docetaxel on days 1, 15, and 29 every 6 weeks. Dose-limiting toxicities (DLTs) were assessed at levels 1 and 2. Pharmacokinetic studies of paclitaxel and docetaxel were conducted at each dose level. Thirty-one patients were enrolled at five dose levels in the first phase and 20 patients in the second phase. There were 10 patients with breast cancer and 21 with NSCLC. There was no DLT at levels 1 or 2. The maximum tolerated dose (MTD) was paclitaxel 175 mg/m(2) and docetaxel 40 mg/m(2). The median (range) numbers of cycles administered were 7.5 (3-30) in the first phase and 7.5 (2-23) in the second. The maximum tolerated dose of paclitaxel and docetaxel administered biweekly is 175 mg/m(2) and 40 mg/m(2), respectively. A complete response was observed in one patient with breast cancer. Complete, partial, and stable disease were reported in three, three, and five patients, respectively. No objective responses were seen.Tribeca Film Festival 2012 — Day Two

Andrews Sisters at The Beacon Theater Monday, July 10, 2012 in New York. (Mandy Patinkin)

It seems the myriad of tents, stands, and other container for films haven’t deterred Tribeca from having a “true film experience.” After a screening of “The Hunt,”

https://colab.research.google.com/drive/1peuwqPNkf3kL-NvdwV_DW_yO_7AcLL5i
https://ello.co/handsoftgoten/post/kdhxo9jdefn06hro4qfxlw
https://colab.research.google.com/drive/1NuQtasmQGQ64AbB-cz3gQFkNFPyaGIF_
https://colab.research.google.com/drive/1erLnLEDmLUvJ5jFSEG-fdibCx4elWA83
https://colab.research.google.com/drive/1M4QCgXFrNmFzYzViPSbLur7i1MlzYm-M
https://ello.co/dispmemsubsi/post/5sdcvu7o1zwzqdrb2qjh8g
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https://colab.research.google.com/drive/1PRwVpBAPIclHw6F_Kt-Mq6acYkQGvNBr

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