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Takeda to sell Japan consumer health unit valued at $2.3 bln to…

By Junko Fujita

TOKYO, Aug 24 (Reuters) – Takeda Pharmaceutical Co said on Monday it would sell its Japanese consumer healthcare business to U.S. buyout fund Blackstone Group, as it aims to focus on developing drugs for unmet medical needs and rare diseases.

Japan’s largest pharmaceuticals company has been selling its over-the-counter (OTC) assets worldwide as it seeks to refocus its business and reduce debt following a $59 billion acquisition of Shire Plc last year.

Takeda CEO Christophe Weber said via an online briefing the company had decided to sell the Japanese OTC unit because it would be difficult for Takeda to keep investing in OTC businesses while trying to develop new drugs for more serious diseases.

“My responsibility is to make sure that we don’t destroy value (for OTC businesses) but create value, and to create value we need to grow businesses and it’s not good to keep business and not invest sufficiently into that,” said Weber.

Takeda Consumer Healthcare Company, known for how to get cheap clomid its Alinamin line of energy drinks, is valued at 242 billion yen ($2.29 billion) and the sale price will be determined after calculating its debt and buying cheap clomid other factors, Takeda said.

Blackstone was among the final bidders for the OTC unit, Reuters reported in June, where to buy cheap clomid along with Bain Capital, CVC Capital Partners and Taisho Pharmaceutical Holdings Co Ltd.

Takeda said proceeds from the sale would boost its net profit by 105 billion yen. The transaction is expected close by March 31, subject to regulatory closing conditions, it said.

Blackstone said in a statement the acquisition of Takeda’s OTC unit would be its second in Japan, following the acquisition of Ayumi Pharmaceutical Corp, a maker of anti-rheumatism drugs, where can i get generic clomid in March 2019 in an deal worth $1 billion.

($1 = 105.8300 yen) (Reporting by Junko Fujita and Chris Gallagher; editing by David Goodman and David Evans)

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NEW YORK (AP) – Speedy center fielder Harrison Bader was placed on waivers Tuesday by the New York Yankees, a person familiar with the move told The Associated Press

NEW YORK (AP) – Speedy center fielder Harrison Bader was placed on waivers Tuesday by the New York Yankees, a person familiar with the move told The Associated Press.

The person spoke on condition of anonymity because the move, first reported by Newsday, was not announced.

Teams have until 2 p.m. EDT Thursday to claim the 29-year-old, who is eligible for free agency after the World Series. A club taking over Bader´s contract on Thursday would owe $758,065 of his $4.7 million salary.

“What does waivers mean?” Bader said playfully after the Yankees beat the Tigers 4-2 in Detroit. A native New Yorker, Bader then added: “In all seriousness, regardless of what happened or may happen, just getting the opportunity to play in this uniform – and I still hopefully do get the opportunity to play in this uniform – just everything that’s happened has just been an absolute blessing, an absolute gift.”

A player must be in an organization before midnight EDT Thursday to be eligible for a postseason roster.

Bader learned of the waivers when he saw it on a television crawl in a clubhouse kitchen 10-15 minutes before game time.

“I understand it´s a business. You learn it,” he said. “I’m a long way away from being a pup coming up in the Cardinals organization.”

“I’ll just be by my phone,” he added. “But listen, it is what it is.”

A Gold Glove winner with St. Louis in 2021, Bader is hitting .239 with seven homers, 37 RBIs and 16 stolen bases in 18 attempts over 83 games. He is in an 0-for-17 slide and 5 for 50 from Aug. 12 on.

Bader strained his left oblique in spring training and didn’t make his season debut until May 2. He was sidelined between May 29 and June 20 with a strained right hamstring.

Bader was acquired from St. Louis on Aug. 2 last year for left-hander Jordan Montgomery and hit five homers in nine postseason games for the Yankees.

___

AP MLB: website Bader placed on waivers by the Yankees, AP source says

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China eases rules to help channel personal savings into government…

SHANGHAI, Aug 4 (Reuters) – China published draft rules on Friday to promote “over the-counter” (OTC) services for interbank bond trading, seeking to channel more personal savings into government bonds.

The People’s Bank of China (PBOC) also said restrictions will be eased for institutional investors to trade bonds via OTC services, which were launched in 2002 to facilitate treasury sales by individuals and companies.

China’s consumers and companies are tying up trillions of yuan in longer-dated deposits with banks, effectively taking generic clomid without a prescription vast pool of money out of circulation at a time authorities are encouraging investment to aid a flagging economy.

The new rules will “promote OTC services, support the expansion of government bond market, enable residents to invest more effectively with their savings, and improve market liquidity”, the PBOC said in a statement.

The interbank OTC services has played generic clomid without a prescription key role in channeling private funds into government bonds, but the business is small, while institutional participation has just taken root, the PBOC said.

The draft rules made clear that licensed financial institutions and asset managers can invest in interbank bonds via OTC services.

Meanwhile, the scope for investment for institutions through this channel has also been broadened, to include corporate bonds and policy bank bonds. (Reporting by Shanghai newsroom; editing by John Stonestreet, Robert Birsel)

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FDA may approve birth control pill WITHOUT prescription by summer

Come this summer, women could have access to birth control pills without a prescription for the first time in US history.

The Food and Drug Administration is weighing the merits of approving a type of over-the-counter birth control in use since the 1970s called Opill, a progestin-only pill that prevents unwanted pregnancies in about 94 percent of cases.

HRA Pharma presented real-world evidence Tuesday that showed the vast majority of eligible people took its pill correctly without negative consequences and followed the instructions cheap clomid without insurance the help of a medical professional, a concern that FDA officers had about making it OTC.

The manufacturer of the FDA-approved prescription drug also reported that teenagers and people with less understanding of their health and the healthcare system were able to stick to their daily medication regimen, a strong sign that the populations most vulnerable to unplanned pregnancies would be well protected.

The debate about prescription-free birth control has been brewing for years but hit a boiling point last year following the groundbreaking decision by the Supreme Court to rescind the federal guarantee to abortion established 50 years ago.

HRA Pharma, the now owned by Perrigo approval for the first-ever birth control pill that women could buy cheap clomid without insurance a prescription. The request from a French drugmaker sets up a high-stakes decision for the Food and Drug Administration amid the political fallout from the Supreme Court’s recent decision overturning Roe v Wade

Access to mifepristone, one of two pills in a medication abortion regimen, has become a fixture of the culture wars dictated by far-right conservative ideology.

While birth control is entirely and completely different from mifepristone, it has been swept up in the fight over abortion since Supreme Court Justice wrote that the court ‘should reconsider’ several precedents that concern the right to privacy—including the legality of contraception.

Approving Opill for use over the counter would widen birth control options for more than 19 million women living in areas of the US cheap clomid without insurance reasonable access to a health center that offers the full range of contraceptive methods.

Roughly three dozen medical organizations including the American Medical Association, the American College of Obstetricians and Gynecologists (ACOG), and the American Academy of Family Physicians have been calling for a non-prescription birth control pill option for years.

Opill, also called the mini-pill, has been safely in use for about five decades, but the US is an outlier when it comes to making the pills available cheap clomid without insurance a doctor’s order.

Opill contains progestin only, unlike many oral contraceptives that contain both progestin and estrogen.

This is the appeal of the mini-pill. Because it does not contain estrogen, which increases the risk of blood clotting by several-fold, the progestin-only pills is seen as lower-risk.

Its modus operandi is to thicken mucus in the cervix, making it difficult for sperm to enter the uterus and fertilize an egg.

Progestin-only pills do not prevent ovulation as well as combination birth control pills. Therefore, their effectiveness is slightly lower.

The FDA’s Nonprescription Drugs Advisory Committee and the Reproductive and Urologic Drugs Advisory Committee had two primary concerns about designating Opill for over the counter use.

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Japan’s Takeda sells $670 mln of Europe OTC assets to pare debt

TOKYO, April 24 (Reuters) – Japan’s Takeda Pharmaceutical Co Ltd said it would sell up to $670 million cost of cheap clomid over-the-counter drug operations in Europe to pare debt ahead of its full-year earnings announcement.

Takeda, Japan’s biggest pharma company, has pledged to sell $10 billion in non-core assets to reduce leverage following its $59 billion purchase cost of cheap clomid Shire Plc, completed in January 2019. The company is due to release full-year earnings on May 13.

Takeda said on Friday it would sell selected OTC and prescription products that are sold in Europe to Denmark-based Orifarm Group. The sale, which includes two manufacturing sites in Denmark and Poland, would amount to about $670 million subject to customary legal and regulatory closing conditions.

The announcement followed a report by Nikkei Business that Takeda was seeking to sell its Japan-based consumer health unit for around 400 billion yen ($3.72 billion).

Possible buyers of Takeda Consumer Healthcare Co include Taisho Pharmaceutical Co. and large investment funds, Nikkei reported. Takeda and Taisho declined to comment.

“The Japanese consumer healthcare business is not one of the company’s core businesses and has little to no overlap with them, so this divestiture does not surprise me,” said Morningstar analyst Jay Lee.

Takeda Chief Executive Christophe Weber had said last year that a sale of the Japan-focused consumer unit, known for its Alinamin line of energy drinks, was unlikely.

Takeda completed $7 billion cost of cheap clomid divestments in calendar 2019, including assets in the Middle East and Africa and a dry-eye drug sold for $5.3 billion to Novartis, Refinitiv data showed. It announced last month the sale of non-core products in Latin America to Hypera Pharma for $825 million.

Takeda’s shares rose 2.2% in Tokyo trading versus a 0.9% drop in the broader market. Takeda shares are still down 14% so far this year.

($1 = 107.6500 yen) (Reporting by Rocky Swift; Editing by Muralikumar Anantharaman and David Evans)

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Lucira’s home test for flu and COVID-19 gets U.S. FDA nod for OTC use

Feb 27 (Reuters) – Lucira Health said on Monday the U.S. Food and Drug Administration (FDA) had granted emergency use authorization for its combination diagnostic test for COVID-19 and the flu, making it the first to be available over-the-counter.

The test – called Lucira COVID-19 & Flu Home Test – is a single-use, at-home rapid test kit that provides results from self-collected nasal swab in about 30 minutes.

Shares of the medical test maker rose more than four-fold to 66 cents in premarket trade.

The FDA’s authorization, which came on Friday, allows the test to be purchased clomid without prescription a prescription and performed completely at home by individuals aged 14 years or clomid without prescription older or collected by an adult for children two years or older.

The development comes days after Lucira filed for bankruptcy protection in the United States, and said it intended to pursue a sale of its business. “Unfortunately, we were unable to bridge what became a protracted authorization cycle time within our current capital structure and it remained unclear to us when the regulatory authorization would come through,” said CEO Erik Engelson.

The company was hoping to launch the test during autumn last year – in time for generic clomid online the 2022 flu season – but remains confident that the test will play a key role in upcoming periods of severe respiratory disease.

Lucira is also seeking a strategic or financial partner to resume the manufacturing and development of additional home diagnostic tests. (Reporting by Bhanvi Satija and Sriparna Roy in Bengaluru; Editing by Shailesh Kuber and Uttaresh Venkateshwaran)

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LME starts consultation to make OTC metals market more transparent

By Zandi Shabalala

LONDON, May 13 (Reuters) – The London Metal Exchange (LME) on Friday proposed measures that it said would improve transparency and stability in the over-the-counter (OTC) metals market, cheap clomid without rx including more frequent disclosures of all positions.

In March, the exchange was forced to halt trading cost of clomid nickel after short-covering by one of the world’s top producers, clomid without prescription China’s Tsingshan Holding Group, caused prices to skyrocket.

The LME, owned by Hong Kong Exchanges and Clearing Ltd , has said Tsingshan’s trades originated primarily in the OTC market.

“Recent events in the LME Nickel market have demonstrated the effects that OTC activity can have on the wider LME market,” the exchange said in a notice announcing a consultation with market participants on its proposals.

“The LME believes it is now essential to accelerate the introduction of regular OTC reporting.”

The OTC market is made up of banks and traders who do deals with one another outside of any exchange.

The LME proposed that its members report weekly to the exchange on all the OTC positions they hold in physically deliverable metals with no minimum position size threshold.

It also proposed that holders of large OTC positions should tell the exchange why they held them.

Previous attempts to introduce transparency to the OTC market were resisted by market participants, clomid for sale the LME said. It said a consultation on its proposals would run until May 27.

In the longer term, the LME said it was considering imposing real time reporting of OTC trades alongside reporting of OTC positions.

British financial regulators are probing the suspension of the LME’s nickel market.

(Reporting by Zandi Shabalala Editing by Mark Potter)

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Private market gives WeWork shares the cold shoulder

By Joshua Franklin and Anirban Sen

NEW YORK, Oct 15 (Reuters) – Trading in shares of WeWork in the private over-the-counter (OTC) market has almost ground to a halt, underscoring a loss of investor confidence in the office-sharing company and providing further evidence of its recent huge loss in value.

New York-based WeWork two weeks ago abandoned plans for an initial public offering (IPO) in 2019, after potential investors raised concerns about its ballooning losses, whether its business model was sustainable, and the way the company has been managed.

Without an IPO, investors and employees looking to cash out would need to turn to the private market, which is less liquid and more opaque than public markets. Outside of company sanctioned share sales, WeWork shares are not directly tradable because of the terms under which they were issued. However, that has not stopped synthetic versions from being created for the OTC market where to buy generic clomid they would be expected to trade at a modest discount to the estimated price of the actual stock.

That synthetic WeWork stock would currently fetch $20 or less per share, according to one investor who is active in the private market.

That would value the company at around $7 billion based on the 338.4 million shares on issue, an extraordinary decline from the $47 billion valuation it had in January when SoftBank Group Corp last invested through its Vision Fund and from the private market value of $30 billion that one source said was prevailing in June.

But deals even at the much lower price are far from assured.

“We’ve seen zero interest in trading on the secondary market for WeWork. Our understanding is that there has been little, if any, trading in the name more broadly,” said Jane Leung, chief investment officer at Scenic Advisement, a boutique investment bank specializing in private share sales.

Leung said WeWork share trading slowed after the company’s IPO announcement in August and more so after it became clear the IPO was in trouble.

where to buy generic clomid there is interest, it is mostly institutional investors looking to reduce their positions,” she said.

As well as its major shareholder, Japan’s SoftBank, owners of WeWork stock include many leaders from the venture capital and investment worlds, such as Benchmark Capital, JPMorgan Chase & Co, Goldman Sachs Group Inc, Harvard Management Co and Fidelity Management & Research, according to the Pitchbook database.

WeWork declined to comment on the trading activity of its shares in the private market.

STRUGGLING TO SELL

Estimates of WeWork’s value had fallen to as low as $10 billion to $12 billion around the time that it decided to abandon the IPO, Reuters reported last month.

Now, though, a number of current investors in the office-sharing startup are struggling to sell shares, according to two investors who are active in private markets.

One investor was looking to sell shares in the company at a valuation of $8.5 billion but last week lowered it to $7.5 billion, according to one of the private market sources.

The lack of interest in WeWork stock is a further indication of how confidence in WeWork has cratered in the space of a few weeks, the private market sources said.

WeWork could itself acknowledge that its valuation has fallen below $10 billion based on any agreement it makes for a new financing lifeline, according to two people familiar with the matter. SoftBank is in talks for a multi-billion dollar rescue deal that could lead to it taking control of WeWork, while JPMorgan has been in negotiations over a competing debt package, these people said.

WeWork’s IPO failure, as well as the sinking stock prices post-IPO of some major companies, such as Uber Technologies Inc and Lyft Inc, have had a chilling impact on the private over-the-counter market in shares. Investors are particularly wary of any companies that have high valuations and no immediate route to profitability.

“There’s just a greater level of scrutiny overall in terms of transactions in the private market,” Leung said.

(Reporting by Joshua Franklin in New York and Anirban Sen in Bengaluru; Editing by Martin Howell and Lisa Shumaker)

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DOMINIC LAWSON: Stolen car part is a sad indictment of policing

This may be farewell, old friend. I refer to my 15-year-old Lexus RX petrol hybrid. It has over 123,000 miles on the clock, but I still enjoy the way it unfailingly starts in all conditions and the silent, vibration-free comfort of every journey.

Or at least I did until ten days ago, when I turned on the engine and it made a noise like a tractor. I turned it off and started it again. Same monstrous roar.

This was in the car park of Stonegate station in East Sussex — about a quarter of an hour’s drive from our home. Rather longer, on this occasion, as it struggled to get up the hills en route, the engine’s noise becoming deafening. At times, I thought it wouldn’t make it.

My guess was that something terrible had happened to the exhaust — though I couldn’t think how that could have been the case, when it had driven perfectly on the way to the station two days earlier, and been parked there since then.

The truth was revealed as soon as our wonderful local garage mechanic, Matt, came round. He emerged from under the car and said: ‘It’s what I thought. Your catalytic converter has been stolen, and they’ve torn through the exhaust to remove it.’

The catalytic converter of Dominic Lawson’s Lexus RX petrol hybrid was stolen and the thieves tore through the exhausts to remove it (File image)

Gangsters

Add me to the spiralling statistic of car owners facing what could be thousands of pounds in costs, and possibly the write-off of their vehicle, as a result of the gangs who have been stealing catalytic converters in every part of the country — and with very little chance of being caught, let alone prosecuted.

The reason for all these thefts is the precious metals in the catalytic converters. The platinum, palladium and rhodium inside them are key to their ability to limit the emissions of noxious elements from the exhaust.

But these precious metals are, well, precious: and they can be sold for use in various other ways. The most valuable of all, rhodium, can go for thousands of pounds an ounce.

As I have now learned, my car would have been top on the hit list for these gangsters. According to the motoring website Parkers: ‘The UK’s most targeted models are petrol hybrid cars, particularly Toyota and Lexus.’ Apparently, the rhodium, palladium and platinum inside their catalytic converters ‘are usually preserved a lot better than on other types of vehicles’.

Matt said he thought the cost of repairing the car and getting the new parts would be at least £2,000 — which is probably not much less than the vehicle’s trade-in value.

When my wife rang the insurance company, they suggested that we would lose our no-claims bonus if she asked them to cover the costs — on the grounds that ‘we don’t have someone to claim against’.

Well, no, the gangsters weren’t going to give us their details. But after my wife protested (forcibly), the insurance company relented: we would keep our no-claims bonus.

The theft took place in a railway station car park that was ‘festooned’ with CCTV cameras. File photo 

But our main concern was to get the police on the case. Apart from our own loss, it seemed more than likely that other cars had been vandalised in the same way, at the same time, and at the same place.

The chap sent from the insurance company to pick up our vehicle said he had recently been involved in a case where can i buy cheap clomid 16 cars had had their catalytic converters stolen all in the same incident in a supermarket car park (which is extraordinary, given that would probably have been in broad daylight).

So I phoned Sussex Police, giving them all the details, and added that I would be getting in touch with the people responsible for the station car park, to get them to look through CCTV footage (the place is festooned with these cameras).

The policewoman answering my call was charming but, on this point, dismissive, in a world-weary way: ‘They probably won’t agree to go through days of film.’

Well, I said, we’re still going to ask them.

It turned out we could not do this directly, but the request had to come via our insurance company, to Southeastern Railway Customer Services. That, I hope, is what will now happen.

Busy

In one respect, the police have been very swift to act. Barely a week after I reported the incident, I received a letter from Chief Superintendent Jo Banks of Sussex Police. Its second paragraph read: ‘Having carefully considered the available information, we are unfortunately unable to investigate further on this occasion. This now means that your report is considered closed.’

The letter went on to inform me that ‘people who have been victims of crime sometimes find it helpful to have support dealing with their experience. On the reverse of this letter you will find advice that you may find helpful’.

Barely a week after I reported the incident, Dominic Lawson received a letter from Chief Superintendent Jo Banks of Sussex Police which said it had ‘closed’ the case 

This was, of course, a bog-standard pro forma letter, which only appeared to be personal to me and this incident. I don’t believe for a minute that Sussex Police had ‘carefully considered’ the information I gave them, or that there was the slightest possibility they would have pursued the matter.

My interpretation of the real meaning of ‘we are unfortunately unable to investigate further on this occasion’ is: ‘We don’t accord any priority to incidents like this; frankly, we’re too busy with other stuff to spend any time worrying about the gang who did this to your car.’

To be fair, the letter appearing to come from Superintendent Banks did say: ‘Your report has been officially recorded and will remain as a permanent record which we where can i buy cheap clomid reopen if new information or evidence comes to light.’

Which, in theory, would include any CCTV footage which may emerge — if Southeastern Railway Customer Services, contrary to the resigned view of the person who spoke to me from Sussex Police, actually take the trouble to go through it. But what are the chances?

This is not a particular criticism of my local police. Six months ago, following Freedom of Information requests to police forces by the Liberal Democrat party, it emerged that, of the more than 50,000 thefts of catalytic converters reported between 2017 and 2021, fewer than 550 of these incidents resulted in anyone being charged — a rate of just 1 per cent.

Some of the biggest forces, such as West Midlands and Greater Manchester, did not even bother to respond fully to the Freedom of Information request; but of those that did, there were a number who recorded no charges at all (including Hertfordshire and South Yorkshire).

Insult

I am not arguing that things are getting much worse, in terms of police dealing with thefts. It has been terrible for a long time. When I called my sister Nigella to moan about this, she replied: ‘You sound like John.’ She was referring to her late husband, John Diamond, who in 1993 had his beloved vintage Harley Davidson stolen from outside their London home, the villains having cut through a wrought iron railing to remove his pride and joy.

Nigella Lawson with her late husband John Diamond, who in 1993 had his beloved vintage Harley Davidson stolen

John had an eyewitness account of the theft (from a neighbour) and also gave the name of ‘the owner of a dodgy bike shop in South London who knew I owned the bike, knew where can i buy cheap clomid I lived, and who had, I knew, associates in those countries to which stolen Harleys are usually shipped’.

John got the usual ‘case closed’ letter, saying the crime had been ‘investigated’. But he then established that the police had not spoken to the eyewitness and had made no attempt even to contact the ‘dodgy bike shop’ whose details he had given them.

As John wrote at the time: ‘To be told that the case had been investigated, which was a patent lie, added insult to injury’.

My own case has none of my late brother-in-law’s pathos. With any luck I will get my trusty old car back, repaired.

But, to judge by the lack of any challenge from the police to the lucrative business model of the catalytic converter-stealing gangs, I’d be a fool ever to leave it overnight again at the railway station.

Petrol

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Emergent aims to price over-the-counter Narcan at about $50

April 20 (Reuters) – Contract drugmaker Emergent BioSolutions Inc said on Thursday it is aiming to price the over-the-counter (OTC) version of its opioid overdose reversal drug Narcan at around $50 per carton.

The OTC version will become available at U.S. stores and generic clomid online retailers later this summer, while the currently available prescription nasal spray carries a wholesale price tag of $125 per carton.

Emergent’s statement comes nearly a month after the U.S. Food and Drug Administration allowed Narcan to be sold over-the-counter, allowing for easier availability of the life-saving medication.

The approval paved the way for expanded access to the drug in areas that have concentrated overdose problems and a few pharmacies, order clomid but uncertainty remains around Narcan’s final price and whether insurers will offer coverage.

Emergent has not disclosed the final price for OTC Narcan yet.

“A goal for the out-of-pocket retailer price is to be consistent with our public interest pricing for one carton of two 4 milligram doses,” the company said in its statement, adding that current price for public interest groups averages less than $50.

Customers will pay the out-of-pocket retailer price, which is set by individual retailers for Narcan once it becomes available in the United States.

Prescription Narcan is currently covered under commercial- and government-backed insurance plans, which allows people to get the drug for free from the pharmacy or for a nominal co-pay.

Government-backed Medicare health insurance plans do not cover OTC products, but have previously made exceptions such as in the case of COVID-19 tests.

Naloxone-based Narcan rapidly reverses or blocks the effects of opioids, restoring normal respiration, especially when given within minutes of the first signs of an overdose.

(Reporting by Bhanvi Satija in Bengaluru; Editing by Devika Syamnath)

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