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Libor demise and Brexit reshape derivatives market, says BIS

November 8, 2023 Insurance by

By Huw Jones

LONDON, Oct 27 (Reuters) – Brexit and the demise of Libor are reshaping the world’s over-the-counter (OTC) interest rate derivatives market, clomid for sale where daily turnover totalled $5.2 trillion in April, down from $6.4 trillion in April 2019, the Bank for International Settlements (BIS) said on Thursday.

“The most significant factor contributing to the decline in turnover is the continuing shift away from Libor for major currencies,” the BIS said in its latest triennial snapshot of the global OTC interest rate derivatives market.

Banks and their clients use interest rate swaps to insure themselves against unexpected moves in borrowing costs.

After banks were fined for trying to rig the London Interbank Offered Rate, clomid price or Libor, the bulk of the benchmark’s permutations were scrapped at the end of 2021 and replaced with rates compiled by central banks.

Replacing Libor shrank turnover in forward rate agreements or cheap clomid without insurance FRAs, a type of derivatives contract, with turnover in dollar FRAs tumbling by 98%.

Sales desks in Britain recorded the highest turnover of interest rate derivatives, at $2.6 trillion, or 46% of global ‘net-gross’ turnover, down from 51% in 2019.

“Turnover in U.S. dollar swaps has partially shifted from sales desks in the United Kingdom to the United States and Asian financial centres,” the BIS said.

“Similarly, turnover in euro swaps has shifted from the United Kingdom to the euro area.”

Brexit from the end of 2020 meant that EU banks could no longer trade OTC derivatives in London, forcing them to trade on platforms in the United States in some cases.

Turnover in euro contracts reached $1.8 trillion per day in April 2022 to 34% of global turnover, up from 25% in 2019, as dollar contracts fell from roughly half of the global market in 2019 to 44% in April.

Turnover of euro rate swaps in Britain fell 18% to $1 trillion over the three years, while turnover by dealers, particularly in Germany and France more than tripled, from $124 billion in 2019 to $385 billion in 2022.

Euro-denominated contracts, excluding FRAs, traded in euro area countries accounted for more than a quarter of the global total, the highest share since 2010, BIS said.

(Reporting by Huw Jones; Editing by Toby Chopra)

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Gold demand falls in Q2 as central bank buying slows, WGC says

November 8, 2023 Insurance by

By Polina Devitt LONDON, Aug 1 (Reuters) – Global gold demand excluding over-the-counter (OTC) trading fell 2% year-on-year to 920.7 metric tons in the second quarter of 2023 as central banks slowed their purchases and consumption by the technology sector remained soft, the World Gold Council (WGC) said on Tuesday.

However, demand from both jewellers, which account for around half of gold demand, and investors, who see bullion as a safe asset during periods of global instability, remained resilient, supporting high prices in April-June, the WGC said in its quarterly demand clomid tablet trends report.

Demand shot to an 11-year high in 2022 thanks to the biggest central bank purchases on record. In the first half of 2023, central banks bought 386.9 metric tons of gold, more than in any January-June period in data going back to 2000, the WGC said. “Buying activity remains widespread and distributed among both emerging and developed countries,” it added.

Purchases of gold bars and where can i get clomid no prescription coins rose, with Turkey a major driver of growth, while outflows from exchange traded funds (ETFs) storing bullion for clomid without dr prescription investors slowed, clomid generic the WGC said. Including OTC trading, conducted directly between two parties rather than via an exchange, total global gold demand rose 7% to 1,255.2 metric tons in the second quarter.

“Although opaque, demand from this sector of the market was apparent as the gold price found firm support even in the face of ETF outflows and a reduction in COMEX net longs,” the WGC said. Investment in gold is on track to rise this year as strong OTC demand makes up for softness in ETFs and a slowing bar and coin sector, it added.

QUARTERLY GOLD DEMAND (tonnes)* Q2 2023 Q1 2023 Q2 2022 y/y % change Jewellery fabrication 491.3 511.5 0 493.5 Technology 70.4 70.1 -10 78.3 – of which electronics 56.4 56.1 -12 64.3 – other Industrial 11.6 11.6 +1 11.4 – dentistry 2.4 2.4 2.6 -10 Investment 256.1 275.9 +20 213.8 – of which bar and coin 277.5 304.5 +6 261.2 – ETFs & similar products -21.3 -28.7 -47.4 Central banks & other inst.

102.9 284.0 -35 158.6 GOLD DEMAND 920.7 -2 1,141.5 944.2 OTC and other 334.5 63.4 +44 232.5 TOTAL DEMAND 1,255.2 +7 1,204.9 1,176.6 * Source: World Gold Council, Gold Demand Trends Q2 2023 (Reporting by Polina Devitt; Editing by Kevin Liffey)

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LME starts consultation to make OTC metals market more transparent

November 8, 2023 Insurance by

By Zandi Shabalala

LONDON, May 13 (Reuters) – The London Metal Exchange (LME) on Friday proposed measures that it said would improve transparency and stability in the over-the-counter (OTC) metals market, including more frequent disclosures of all positions.

In March, the exchange was forced to halt trading of nickel after short-covering by one of the world’s top producers, cheap clomid pills China’s Tsingshan Holding Group, caused prices to skyrocket.

The LME, owned by Hong Kong Exchanges and generic clomid without rx Clearing Ltd , has said Tsingshan’s trades originated primarily in the OTC market.

“Recent events in the LME Nickel market have demonstrated the effects that OTC activity can have on the wider LME market,” the exchange said in a notice announcing a consultation with market participants on its proposals.

“The LME believes it is now essential to accelerate the introduction of regular OTC reporting.”

The OTC market is made up of banks and traders who do deals with one another outside of any exchange.

The LME proposed that its members report weekly to the exchange on all the OTC positions they hold in physically deliverable metals with no minimum position size threshold.

It also proposed that holders of large OTC positions should tell the exchange why they held them.

Previous attempts to introduce transparency to the OTC market were resisted by market participants, the LME said. It said a consultation on its proposals would run until May 27.

In the longer term, the LME said it was considering imposing real time reporting of OTC trades alongside reporting of OTC positions.

British financial regulators are probing the suspension of the LME’s nickel market.

(Reporting by Zandi Shabalala Editing by Mark Potter)

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Takeda to sell Japanese consumer health unit to Blackstone for $2.3…

November 8, 2023 Loans by

TOKYO, Aug 24 (Reuters) – Takeda Pharmaceutical Co has agreed to sell its Japanese consumer healthcare business to U.S. investment fund Blackstone Group for 242 billion yen ($2.3 billion), Japan’s largest drugmaker said on Monday.

The sale cost of clomid Takeda Consumer Healthcare Company, which makes over-the-counter (OTC) drugs and health products, is expected to close by March 31, subject to regulatory closing conditions, the company said in a statement.

Takeda has been reducing its OTC assets worldwide as it seeks to refocus its business and reduce debt after its $59 billion acquisition cost of clomid Shire. ($1 = 105.8300 yen) (Reporting by Chris Gallagher Editing by David Goodman )

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McKesson to buy pharma tech firm Rx Savings for up to $875 mln

November 8, 2023 Loans by

Sept 19 (Reuters) – Drug distributor McKesson Corporation said on Monday it would acquire private pharma technology firm Rx Savings Solutions for up to $875 million.

The company helps health insurers and employers seek lower cost prescription medicines, and also provides ongoing medication reminders to help improve adherence to prescriptions.

“Rx Savings Solutions´ offerings for employers and patients will strengthen McKesson´s ability to help solve the most common medication challenges related to access, affordability and adherence,” McKesson Chief Executive Officer Brian Tyler said.

The transaction, which includes a $600 million upfront payment and can i order generic clomid up to $275 million contingent on Rx Savings’ financial performance through 2025, is expected to close in the second half of fiscal year 2023. (Reporting by Leroy Leo and can i purchase generic clomid Khushi Mandowara in Bengaluru; Editing by Vinay Dwivedi)

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Libor demise and Brexit reshape derivatives market, says BIS

November 8, 2023 Loans by

By Huw Jones

LONDON, Oct 27 (Reuters) – Brexit and the demise of Libor are reshaping the world’s over-the-counter (OTC) interest rate derivatives market, where can i buy cheap clomid daily turnover totalled $5.2 trillion in April, down from $6.4 trillion in April 2019, the Bank for International Settlements (BIS) said on Thursday.

“The most significant factor contributing to the decline in turnover is the continuing shift away from Libor for major currencies,” the BIS said in its latest triennial snapshot of the global OTC interest rate derivatives market.

Banks and their clients use interest rate swaps to insure themselves against unexpected moves in borrowing costs.

After banks were fined for trying to rig the London Interbank Offered Rate, or Libor, the bulk of the benchmark’s permutations were scrapped at the end of 2021 and replaced with rates compiled by central banks.

Replacing Libor shrank turnover in forward rate agreements or FRAs, a type of derivatives contract, with turnover in dollar FRAs tumbling by 98%.

Sales desks in Britain recorded the highest turnover of interest rate derivatives, at $2.6 trillion, or 46% of global ‘net-gross’ turnover, down from 51% in 2019.

“Turnover in U.S. dollar swaps has partially shifted from sales desks in the United Kingdom to the United States and Asian financial centres,” the BIS said.

“Similarly, turnover in euro swaps has shifted from the United Kingdom to the euro area.”

Brexit from the end of 2020 meant that EU banks could no longer trade OTC derivatives in London, forcing them to trade on platforms in the United States in some cases.

Turnover in euro contracts reached $1.8 trillion per day in April 2022 to 34% of global turnover, up from 25% in 2019, as dollar contracts fell from roughly half of the global market in 2019 to 44% in April.

Turnover of euro rate swaps in Britain fell 18% to $1 trillion over the three years, while turnover by dealers, particularly in Germany and France more than tripled, from $124 billion in 2019 to $385 billion in 2022.

Euro-denominated contracts, excluding FRAs, traded in euro area countries accounted for clomid more than a quarter of the global total, the highest share since 2010, BIS said.

(Reporting by Huw Jones; Editing by Toby Chopra)

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FDA proposes rule to make many hearing aids cheaper

November 8, 2023 Loans by

Oct 19 (Reuters) – The U.S. Food and Drug Administration on Tuesday proposed creation of a new category of over-the-counter (OTC) hearing aids to be sold directly to millions of Americans in an effort to make the devices more affordable.

White House spokeswoman Jen Psaki said the proposed rules should be finalized next year and should increase competition to drive down prices, so the devices cost “hundreds instead of thousands of dollars.”

The changes “will help millions of Americans with mild to moderate healing loss get access to cheaper and more convenient access to hearing aids,” she told reporters, adding just one-fifth of the estimated 37.5 million Americans who have trouble hearing use such aids.

The rule allows greater reach to communities of color that have been typically lacked access to hearing aids, said Xavier Becerra, secretary of Health and Human Services.

Under the proposal, cheap clomid without rx hearing aids generic clomid for sale severe hearing loss or for users younger than 18 would remain as prescription devices.

The department will take comments on the proposed rule for 90 days and plan to implement the rule 60 days after finalizing it.

“Finalizing this remains a top priority for the agency,” said Jeff Shuren, where to get clomid director of the FDA’s Center for Devices and Radiological Health, said during a press call.

Representative Debbie Dingell called the announcement “a major step forward for hearing health and will increase the accessibility of affordable hearing aid options for those who need them.”

The proposed rule follows an instruction in President Joe Biden’s broad competition executive order, which had told the Department of Health and Human Services to “promote the wide availability of low-cost hearing aids,” among many other instructions aimed at a wide variety of industries. (Reporting by Manojna Maddipatla in Bengaluru and Diane Bartz and Trevor Hunnicutt in Washington; Editing by Shinjini Ganguli and Nick Zieminski)

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Perrigo unit asks FDA to approve first ever OTC birth control pill

November 8, 2023 Loans by

July 11 (Reuters) – Perrigo Company said on Monday its unit HRA Pharma has asked the U.S. Food and Drug Administration (FDA) to approve a daily birth control pill for over-the-counter (OTC) sale, the first such request for this type of contraception.

The application from the HRA comes on the back of the U.S. Supreme Court’s decision in June to overturn the 1973 Roe v. Wade case that legalized abortion nationwide.

The contraceptive is currently a prescription drug sold under brand Opill.

HRA Pharma expects the regulator to hold an advisory committee meeting and approve the application in the first half of 2023, a period of about 10 months is typical for such approval requests, said Frederique Welgryn, HRA Pharma’s chief strategic operations and innovation officer.

“The timing is a bit coincidental. We have been working on that application for the last seven years,” Welgryn said.

The FDA declined to comment on the submission.

Meanwhile, Iffath Abbasi Hoskins, president of the American College of Obstetricians and Gynecologists, said the submission was a positive.

“We know that birth control is not a solution to abortion bans, as people need abortion care for many reasons,” Hoskins said, but added that the pill could still help more people to “control their own reproductive futures”.

Currently, the only contraception drugs available for women without a prescription are emergency oral pills that where can i get clomid no prescription be taken within three days after having unprotected sex.

Abortion rights activists have stepped up calls to make mifepristone, which in combination with misoprostol induces an abortion up to 10 weeks into a pregnancy, available OTC.

The non-estrogen Opill has been used with where can i get clomid no prescription since it was FDA-approved in 1973. Perrigo said scientific evidence has shown progestin-only pills, such as Opill, are effective at preventing pregnancy and safe for most women to use. (Reporting by Leroy Leo in Bengaluru; Editing by Krishna Chandra Eluri and Shinjini Ganguli)

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Health Canada says more heartburn medicines being recalled after…

November 8, 2023 Loans by

Sept 25 (Reuters) – Health Canada said on Wednesday four companies were recalling popular heartburn drug ranitidine, known by its brand name Zantac, after presence of a probable cancer-causing impurity was found in some of the drugs.

The companies recalling the drugs include Apotex Inc, Pro Doc Limitée, Sanis Health Inc and Sivem Pharmaceuticals ULC, along with Novartis AG’s recall, which was announced last week.

Branded versions of the drug such as Sanofi SA’s Zantac are available for over-the-counter (OTC) sale in Canada, while generic versions are available for sale both OTC and with prescription. (Reporting by Manas Mishra in Bengaluru; Editing by Shounak Dasgupta)

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Reuters Health News Summary

November 8, 2023 Insurance by

Following is a summary of current health news briefs.

US FDA staff raises concerns over OTC use of Perrigo’s birth control pill

The U.S. health regulator’s reviewers on Friday raised concerns around allowing Perrigo Co’s birth control drug over the counter, saying switching to non-prescription sale could lead to inappropriate usage by consumers. Perrigo’s Opill, which is currently approved for prescription use, would be the first OTC non-estrogen contraceptive pill in the United States if approved.

UNICEF: More than 1 million polio vaccines destroyed in Sudan

More than 1 million polio vaccines intended for cost of generic clomid no prescription children have been destroyed as a result of looting in Sudan during the upsurge in violence since April, the U.N. children’s agency UNICEF told Reuters on Friday. “A number of cold chain facilities have been looted, damaged and destroyed, including over a million polio vaccines in South Darfur,” Hazel De Wet, deputy director of the Office of Emergency Programmes, UNICEF told Reuters in an email.

US CDC chief Rochelle Walensky stepping down in June

U.S. Centers for Disease Control and Prevention (CDC) Director Dr. Rochelle Walensky, a top health official who oversaw the agency’s contentious response where to buy generic clomid the COVID-19 pandemic, is leaving the institution at the end of June, the CDC said on Friday. Walensky led the institution for two years while the pandemic was at its height. Her agency was pivotal in ushering in the adoption of vaccine recommendations that slowed the spread of a virus that has killed more than a million Americans and is still killing more than a thousand a week.

CDC to scale back data collection as US ends COVID health emergency

The U.S. Centers for Disease Control and Prevention (CDC) said on Friday it would stop reporting or monitoring COVID-19 case data and transmission rates after the government ends the pandemic’s public health emergency designation next week. The agency will stop using its color-coded COVID-19 Community Levels (CCL) system, which relies on those metrics to track the spread of the virus and will instead primarily rely on hospital admission data.

Cigna’s health insurance strength drives profit forecast raise

Cigna Group on Friday raised its annual profit forecast after lower medical costs at the company’s health insurance business helped it beat estimates in the first quarter, lifting shares 7.5% in morning trade. The health insurer also cut the midpoint of its 2023 medical cost ratio – or spending on claims as a percentage of premiums – by 10 basis points to between 81.5% and 82.3%.

WHO declares end to COVID global health emergency

The World Health Organization ended the global emergency status for COVID-19 on Friday more than three years after its original declaration, and said countries should now manage the virus that killed more than 6.9 million people along with other infectious diseases. The global health agency’s Emergency Committee met on Thursday and where can i buy generic clomid recommended the UN organization declare an end to the coronavirus crisis as a “public health emergency of international concern” – its highest level of alert – which has been in place since Jan. 30, 2020.

North Carolina’s Republican-led legislature passes 12-week abortion ban

North Carolina’s Republican-controlled legislature passed a bill on Thursday that limits the window for most abortions to 12 weeks, down from 20, which could sharply reduce access to the procedure for millions of women across the U.S. south. The measure now heads to Democratic Governor Roy Cooper, who has vowed to veto it, clomid generic following the Senate’s 29-20 approval along party lines, a day after the state House of Representatives passed it in a similar party-line vote.

EU needs tiered drug pricing to improve patient access, Bayer exec says

The European Union should put mechanisms in place to allow drugmakers to charge higher prices in wealthy European countries and lower prices in poorer nations to assure more equitable patient access to life saving medicines, Bayer’s global pharmaceuticals head said in an interview. That might be accomplished in part by restricting drug importation within the EU, Stefan Oelrich, head of Bayer’s pharmaceuticals unit, told Reuters on Thursday.

FibroGen’s anemia drug fails to meet main goal in late-stage trial

FibroGen Inc said on Friday its anemia drug had failed to meet the main goal in a late-stage trial, sending its shares tumbling nearly 12% before the bell. The miss is the latest setback for the company whose application seeking approval for the drug to treat anemia in kidney disease patients was rejected by the U.S. Food and Drug Administration in 2021 seeking additional data.

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