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Takeda to sell Japan consumer health unit valued at $2.3 bln to…

By Junko Fujita

TOKYO, Aug 24 (Reuters) – Takeda Pharmaceutical Co said on Monday it would sell its Japanese consumer healthcare business to U.S. buyout fund Blackstone Group, as it aims to focus on developing drugs for unmet medical needs and rare diseases.

Japan’s largest pharmaceuticals company has been selling its over-the-counter (OTC) assets worldwide as it seeks to refocus its business and reduce debt following generic clomid without a prescription $59 billion acquisition of Shire Plc last year.

Takeda CEO Christophe Weber said via an generic clomid online briefing the company had decided to sell the Japanese OTC unit because it would be difficult for Takeda to keep investing in OTC businesses while trying to develop new drugs for where can i buy clomid more serious diseases.

“My responsibility is to make sure that we don’t destroy value (for OTC businesses) but create value, and to create value we need to grow businesses and it’s not good to keep business and not invest sufficiently into that,” said Weber.

Takeda Consumer Healthcare Company, known for its Alinamin line of energy drinks, is valued at 242 billion yen ($2.29 billion) and the sale price will be determined after calculating its debt and other factors, Takeda said.

Blackstone was among the final bidders for the OTC unit, Reuters reported in June, along with Bain Capital, generic clomid without rx CVC Capital Partners and Taisho Pharmaceutical Holdings Co Ltd.

Takeda said proceeds from the sale would boost its net profit by 105 billion yen. The transaction is expected close by March 31, subject to regulatory closing conditions, it said.

Blackstone said in a statement the acquisition of Takeda’s OTC unit would be its second in Japan, following the acquisition of Ayumi Pharmaceutical Corp, a maker of anti-rheumatism drugs, in March 2019 in an deal worth $1 billion.

($1 = 105.8300 yen) (Reporting by Junko Fujita and Chris Gallagher; editing by David Goodman and David Evans)

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U.S. FDA delays panel meeting on Perrigo’s OTC birth control pill

WASHINGTON, Oct 26 (Reuters) – The U.S. Food and Drug Administration has delayed a meeting cost of generic clomid no prescription its advisory panel to discuss Perrigo Co Plc’s over-the-counter (OTC) contraceptive, the drugmaker said on Wednesday.

The meeting, scheduled for Nov. 18, was delayed to review additional information, and no new date has yet been set, in a setback for what was expected to be the first approved daily OTC birth control pill in the United States.

Contraceptives have been in focus since abortion rights were sharply curtailed by the U.S. Supreme Court’s decision about four months ago to overturn the landmark Roe v Wade ruling.

The health regulator had also extended the decision date for a possible approval decision by 90 days, Perrigo said.

“The meeting has been postponed to allow the agency additional time to review new information. The postponement does not indicate or affect any decision regarding the application,” said an FDA spokesperson.

“The FDA will announce advisory committee meeting updates in the Federal Register and remains committed to a timely review cost of generic clomid no prescription this application,” the spokesperson added.

The drug, Opill, has been used with a prescription since its approval in 1973.

A spokesperson for Perrigo said the company still expects a decision in 2023. (Reporting by Manas Mishra in Bengaluru, Trevor Hunnicutt, and Ahmed Aboulenein in Washington; Editing by Vinay Dwivedi, Sriraj Kalluvila and Cynthia Osterman)

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Forex derivatives nudged out into the open as regulations increase…

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By Laura Matthews

NEW YORK, June 20 (Reuters) – Foreign-exchange investors are moving more of their over-the-counter (OTC) derivatives trades to lookalike products on exchanges to avoid higher costs due to recent global regulations, helping inject transparency into a multitrillion-dollar market that is largely hidden from the public eye.

The growing interest in clearing trades through an exchange comes as regulations capture more users of these contracts, bolstering the need to shift away from bilateral trading and manage rising compliance cost.

“There is more transparency, lower margin requirement overall (in trading listed products), which is a benefit for asset managers and hedge funds in leveraging their positions,” said Ben Feuer, head of FX trading and head of sales trading at Societe Generale in New York.

The gradual behavioral change in FX derivatives trading is being caused by increasing margin and collateral costs, said Joe Midmore, chief commercial officer at OpenGamma, a derivatives analytics firm.

Effective September 2022, buy-side firms with uncleared OTC derivatives totaling at least $8 billion are subject to the regulations – set by the Basel Committee on Banking Supervision and the International Organization of Securities Commissions – and have to ensure there is enough margin to cover the risk of a default by a counterparty to the transaction.

OTC derivatives are privately negotiated contracts while cleared derivatives, though bilaterally negotiated, are booked with a clearinghouse such as a listed exchange. The new margin rules exempt cleared trades.

Higher interest rates make posting margin more expensive.

“Lots of exchange salespeople have been going out to investors for a long time saying ‘look at how much more efficient trading in listed futures is,’ but it didn’t matter until now when interest rates are 5% instead of zero,” said Michael Riddle, CEO at Eris Innovations which partners with the CME Group and other exchanges to develop futures and options products.

The shift is most acute for buy-side firms that have to post margin for the first time, said Paul Houston, head of FX markets at CME Group.

“They will also incur the operational, legal and custody costs of setting up margin facilities as well as the capital costs of posting margin,” Houston said.

CME’s listed FX futures and options market now trades an average daily volume of $85 billion versus $76 billion in 2021, indicating more investors are using exchange-traded derivatives to replace OTC trades where buy cheap clomid possible.

That is still a fraction of the $7.5 trillion that trades daily in the FX markets, the vast majority of which happens OTC.

British clearing house LCH’s ForexClear also had a record May for FX options, surpassing $200 billion in notional value, meaning the total value of a derivatives trade, for the first time.

“For the buy-side, FX clearing materially lowers counterparty risk, enables portfolio optimization and provides operational benefits,” said James Pearson, head of ForexClear.

GROWING ACCEPTANCE

Some 60 firms started trading FX futures and options at the CME Group for the first time this year, more than two-thirds of which are buy-side clients, according to CME data. Last year, 300 firms were trading new instruments for the first time.

An estimated 775 firms came under the scope of the new rules last September, according to ISDA.

Some clients of Record Financial Group, a specialist currency and asset manager, were exploring listed alternatives while others were adjusting their risk management programs to “stay within or under the regulatory threshold,” said the firm’s head of sales, Tom Arnold.

Joe Spiro, director of product management at Hazeltree, said as a firm’s exposure grows more may have to adhere to the new rules, widening the appeal for trading on exchanges.

Investors can also now transact on a relationship basis as they do in the OTC space and access clearing.

For instance, some 274,000 contracts in privately negotiated blocks and exchange-for-related-positions (EFRPs), products that allow users to trade on a disclosed, relationship basis against their liquidity providers and access clearing, were traded on CME on March 8, up 23% from the previous record in December.

Client clearing of nondeliverable forwards at ForexClear for January to May reached $261 billion, 58% higher than the corresponding period in 2022.

Not all see the need to shift even with higher costs and not all derivative products have a cleared alternative, which limits broader adoption.

Exchange-traded futures contracts have a fixed settlement date relative to OTC forwards, making them unattractive to some investors, said Peter Vassallo, a portfolio manager for the currencies team at BNP Paribas Asset Management.

There are also concerns that pushing more trades to the clearinghouse will consolidate risk rather than reduce it.

“There is inherently risk involved in lots of people transacting derivatives with each other,” said Riddle. “And there is no model that removes all that risk, it only changes where buy cheap clomid it is, but can mitigate it.”

(Reporting by Laura Matthews in New York Additional reporting by Shankar Ramakrishnan in New York Editing by Megan Davies and Matthew Lewis)

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Private market gives WeWork shares the cold shoulder

November 7, 2023 Loans rx clomid by clemmieroark

By Joshua Franklin and Anirban Sen

NEW YORK, Oct 15 (Reuters) – Trading in shares of WeWork in the private over-the-counter (OTC) market has almost ground to a halt, underscoring a loss of investor confidence in the office-sharing company and providing further evidence of its recent huge loss in value.

New York-based WeWork two weeks ago abandoned plans for an initial public offering (IPO) in 2019, after potential investors raised concerns about its ballooning losses, whether its business model was sustainable, and the way the company has been managed.

Without an IPO, investors and employees looking to cash out would need to turn to the private market, which is less liquid and more opaque than public markets. Outside of company sanctioned share sales, WeWork shares are not directly tradable because of the terms under which they were issued. However, that has not stopped synthetic versions from being created for the OTC market where to buy generic clomid they would be expected to trade at a modest discount to the estimated price of the actual stock.

That synthetic WeWork stock would currently fetch $20 or less per share, according to one investor who is active in the private market.

That would value the company at around $7 billion based on the 338.4 million shares on issue, an extraordinary decline from the $47 billion valuation it had in January when SoftBank Group Corp last invested through its Vision Fund and from the private market value of $30 billion that one source said was prevailing in June.

But deals even at the much lower price are far from assured.

“We’ve seen zero interest in trading on the secondary market for WeWork. Our understanding is that there has been little, if any, trading in the name more broadly,” said Jane Leung, chief investment officer at Scenic Advisement, a boutique investment bank specializing in private share sales.

Leung said WeWork share trading slowed after the company’s IPO announcement in August and more so after it became clear the IPO was in trouble.

“where to buy generic clomid there is interest, it is mostly institutional investors looking to reduce their positions,” she said.

As well as its major shareholder, Japan’s SoftBank, owners of WeWork stock include many leaders from the venture capital and investment worlds, such as Benchmark Capital, JPMorgan Chase & Co, Goldman Sachs Group Inc, Harvard Management Co and Fidelity Management & Research, according to the Pitchbook database.

WeWork declined to comment on the trading activity of its shares in the private market.

STRUGGLING TO SELL

Estimates of WeWork’s value had fallen to as low as $10 billion to $12 billion around the time that it decided to abandon the IPO, Reuters reported last month.

Now, though, a number of current investors in the office-sharing startup are struggling to sell shares, according to two investors who are active in private markets.

One investor was looking to sell shares in the company at a valuation of $8.5 billion but last week lowered it to $7.5 billion, according to one of the private market sources.

The lack of interest in WeWork stock is a further indication of how confidence in WeWork has cratered in the space of a few weeks, the private market sources said.

WeWork could itself acknowledge that its valuation has fallen below $10 billion based on any agreement it makes for a new financing lifeline, according to two people familiar with the matter. SoftBank is in talks for a multi-billion dollar rescue deal that could lead to it taking control of WeWork, while JPMorgan has been in negotiations over a competing debt package, these people said.

WeWork’s IPO failure, as well as the sinking stock prices post-IPO of some major companies, such as Uber Technologies Inc and Lyft Inc, have had a chilling impact on the private over-the-counter market in shares. Investors are particularly wary of any companies that have high valuations and no immediate route to profitability.

“There’s just a greater level of scrutiny overall in terms of transactions in the private market,” Leung said.

(Reporting by Joshua Franklin in New York and Anirban Sen in Bengaluru; Editing by Martin Howell and Lisa Shumaker)

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These are the cars being targeted by catalytic converter thieves

November 7, 2023 Insurance cheap clomid without prescription by clemmieroark

Thefts of catalytic converters from vehicles parked on the street and in driveways are on the rise, an insurer has warned this week.

Criminals have in recent years preyed on the exhaust devices as they contain valuable metal parts that where can i buy generic clomid be sold at a premium.

Records show that thefts declined when the UK went into lockdown from March. However, there’s been a ‘significant’ rise since June, says Admiral – and it has named the four cars organised criminals are identifying as prime targets.

Catalytic converter thefts is becoming a huge crime problem in the UK.

The motor insurer said it received a massive 400 claims in January alone for damage caused to vehicles when thieves had ripped the emissions-reducing devices from the underside of their petrol-powered cars.

And that’s just one insurance provider among handfuls operating in the country.

Admiral said there had been a dip in claims of this type as more people stayed at home in the first lockdown restrictions.

It said just 52 claims were made in April – an 87 per cent decline in thefts.

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Unfortunately, these types of thefts are dramatically rising again as restrictions in some parts of the country have eased, says Lorna Connelly, head of claims at Admiral.

‘The increase since June has been significant, and shows thieves are back to stealing the precious metals found in catalytic converters in some cars, which are then being sold on for a profit,’ she explained.

And criminals have models that they have earmarked for having the best-quality parts.

All are hybrid cars, which are ripe for thieves as the catalytic converters contain a higher concentration of precious metals and are generally less corroded.

Admiral says data shows the most susceptible hybrid models are the Honda Jazz, Toyota Prius, Toyota Auris and Lexus RX of all generations and ages.

Hybrid cars are ripe for thieves as the catalytic converters contain a higher concentration of precious metals and are generally less corroded. It’s no surprise then that the Toyota Prius – the most-bought hybrid in the UK – is among the list of cars criminals are preying on

Honda’s hybrid version of the Jazz is also on the shopping list of these organised criminals. The Jazz is popular among older drivers and therefore tend to have accumulated fewer miles, meaning their catalytic converters will be in good condition

The Toyota Auris hybrid (left) – the sister car to the Prius – has also been identified by Admiral as a prime target. The Lexus RX hybrid SUV (right) is another model that’s often preyed on by thieves of catalytic converters

Admiral’s warning comes after an investigation by BBC Radio 5 Live into the spike in catalytic converter crime earlier this year.

It calculated that thefts of the devices from the underside of cars had risen six-fold in 2019 with 13,000 reported cases in England and Wales – up from 2,000 the year previous.

It found that criminal gangs stealing catalytic converters are predominantly operating in the capital, though footage of thefts taking place in other locations – which have been featured on MailOnline and This is Money – show that it is spreading outside London.

In an added nasty twist, the BBC said criminals are actively going after vehicles owned by NHS staff – because they are parked for prolonged periods during shifts, giving them ample time to remove the devices.

Why are catalytic converters so valuable?

Catalytic converters – which are fitted to all petrol cars manufactured from 1993 – are there to reduce the harmful pollutants emitted from vehicle exhaust pipes.

They do this by taking the gases produced and converting them into water vapour and less harmful emissions via a series of chemical reactions.

The devices are made up of an array of valuable materials including palladium, rhodium and platinum – and criminal gangs are well aware of this small fortune stored beneath your vehicle.

Currently, palladium is even more valuable than gold, having doubled over two years, while rhodium is more than four times higher in value than gold, according to a recent Money Mail investigation.

It found that a Troy ounce (1.1 ounce) of gold is worth $1,731 (£1,392), while palladium sells for $1,914 (£1,539).

Rhodium, which is sold in normal ounces, was priced at $8,300 (£6,675) an ounce in June.

Platinum is around half the value of gold currently.

With gangs likely to have regular buyers for the metals lined-up, it has simply become a case of sawing the devices off cars as quickly as possible to escape undetected.

‘Year on year we’ve seen an increase in this type of theft so despite the drop in the number of stolen catalytic converters earlier in the year, it looks like thefts are now rising again at a worrying rate,’ Connelly added.

‘Regardless of which car you own, you should do everything you where can i buy generic clomid to make sure it’s parked in a safe and secure place, especially at night, to reduce the risk of your car being affected.’

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CVS Health raises forecast as insurance business, OTC COVID tests…

November 7, 2023 Loans where can i buy generic clomid by clemmieroark

Aug 3 (Reuters) – CVS Health Corp on Wednesday raised its full-year profit forecast after strength in its insurance business and sales of COVID-19 over-the-counter test kits helped the company report a 6% jump in second-quarter earnings.

The largest U.S. pharmacy chain’s retail and long-term care segment revenue rose 6.3%, helped by the sale of OTC test kits and the impact of the flu season, which helped offset lower COVID-19 vaccinations and diagnostic testing.

Its insurance business reported an 11% growth in revenue as well as a decrease in medical benefit ratio, get clomid which is the costs it incurs as a percentage of premiums.

CVS raised its adjusted profit outlook to $8.40-$8.60 per share from $8.20-$8.40 per share forecast earlier.

Net income for cheap clomid tablets the quarter ended June 30 rose to $2.96 billion, or $2.23 per share, from $2.79 billion, or $2.10 per share a year earlier. (By Leroy Leo and Bhanvi Satija in Bengaluru; Editing by Vinay Dwivedi)

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FDA proposes rule to make many hearing aids cheaper

November 7, 2023 Loans generic clomid tablets by clemmieroark

Oct 19 (Reuters) – The U.S. Food and Drug Administration on Tuesday proposed creation of a new category of over-the-counter (OTC) hearing aids to be sold directly to millions of Americans in an effort to make the devices more affordable.

White House spokeswoman Jen Psaki said the proposed rules should be finalized next year and should increase competition to drive down prices, so the devices cost of generic clomid no prescription “hundreds instead of thousands of dollars.”

The changes “will help millions of Americans with mild to moderate healing loss get access to cheaper and more convenient access to hearing aids,” she told reporters, adding just one-fifth cost of generic clomid no prescription the estimated 37.5 million Americans who have trouble hearing use such aids.

The rule allows greater reach to communities of color that have been typically lacked access to hearing aids, said Xavier Becerra, secretary cost of generic clomid no prescription Health and Human Services.

Under the proposal, hearing aids for severe hearing loss or for users younger than 18 would remain as prescription devices.

The department will take comments on the proposed rule for 90 days and plan to implement the rule 60 days after finalizing it.

“Finalizing this remains a top priority for the agency,” said Jeff Shuren, director of the FDA’s Center for Devices and Radiological Health, said during a press call.

Representative Debbie Dingell called the announcement “a major step forward for hearing health and will increase the accessibility of affordable hearing aid options for those who need them.”

The proposed rule follows an instruction in President Joe Biden’s broad competition executive order, which had told the Department of Health and Human Services to “promote the wide availability of low-cost of generic clomid no prescription hearing aids,” among many other instructions aimed at a wide variety of industries. (Reporting by Manojna Maddipatla in Bengaluru and Diane Bartz and Trevor Hunnicutt in Washington; Editing by Shinjini Ganguli and Nick Zieminski)

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RAY MASSEY: Lexus joins the big boys with its hybrid RX SUV

November 7, 2023 Loans cheap clomid no prescription by clemmieroark

Amazing to think it’s 30 years since upmarket car brand Lexus was launched by the Japanese car giant Toyota.

Big in Japan and the U.S., Lexus remains a niche player in the UK, targeting discerning drivers who want something a little different.

It’s sold about 200,000 cars here since 1990 and this year is looking at a record 16,000 sales.

Well-padded: The new Lexus RX SUV blends petrol and electric for greater fuel efficiency

So to help celebrate its three decades on the road I’ve been for a spin in the new 5th generation Lexus RX SUV.

Launched in 1998, it has sold 3 million worldwide since then. It’s been a while since I’ve driven a Lexus so I was taken aback by the huge size of the RX.

But it’s taking on big-boned rivals such as the Audi Q7 and Volvo XC90, so size does matter.

LME WEEK-LME looking at fee structure to address cheaper OTC…

November 7, 2023 Loans where to buy cheap clomid by clemmieroark

LONDON, Oct 9 (Reuters) – The London Metal Exchange (LME) is looking at its fee structure where to buy cheap clomid address the fact that over-the-counter (OTC) trading is cheaper than trading on the exchange, the LME’s chief executive said on Monday.

The 146-year-old LME was forced to halt nickel trading and cancel all deals in March last year after a wild spike in prices caused partly by large OTC short nickel positions.

Since then the exchange, the world’s oldest and largest market for industrial metals, has imposed measures requiring members where to buy cheap clomid report all OTC positions.

The LME has said that the market would benefit from more trading migrating to its electronic platform rather than to telephone-based trading or OTC markets.

During a panel discussion on Monday on the future of the LME nickel contract, which saw trading volumes tumble after last year’s crisis, LME CEO Matthew Chamberlain noted that people sometimes ask him why OTC trading is cheaper than on the LME.

“That’s one area we’re looking at,” Chamberlain said, giving no details.

The LME requires institutions that book OTC trades that use LME prices as a benchmark where to buy cheap clomid pay a fee where to buy cheap clomid the LME of $1.14 per equivalent LME lot, which compares to all-in fees of $2.70 per lot paid for exchange trading.

The LME is owned by Hong Kong Exchanges and Clearing Ltd. (Reporting by Eric Onstad; Editing by Sharon Singleton)

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Lucira’s home test for flu and COVID-19 gets U.S. FDA nod for OTC use

November 7, 2023 Insurance how to get cheap clomid by clemmieroark

Feb 27 (Reuters) – Lucira Health said on Monday the U.S. Food and Drug Administration (FDA) had granted emergency use authorization for its combination diagnostic test for COVID-19 and the flu, making it the first to be available over-the-counter.

The test – called Lucira COVID-19 & Flu Home Test – is a single-use, at-home rapid test kit that provides results from self-collected nasal swab in about 30 minutes.

Shares of the medical test maker rose more than four-fold to 66 cents in premarket trade.

The FDA’s authorization, which came on Friday, allows the test to be purchased without a prescription and cheap clomid pill performed completely at home by individuals aged 14 years or older or collected by an adult for children two years or older.

The development comes days after Lucira filed for bankruptcy protection in the United States, and said it intended where to buy generic clomid pursue a sale of its business. “Unfortunately, we were unable to bridge what became a protracted authorization cycle time within our current capital structure and it remained unclear to us when the regulatory authorization would come through,” said CEO Erik Engelson.

The company was hoping to launch the test during autumn last year – in time for generic clomid without rx the 2022 flu season – but remains confident that the test will play a key role in upcoming periods of severe respiratory disease.

Lucira is also seeking a strategic or financial partner to resume the manufacturing and development of additional home diagnostic tests. (Reporting by Bhanvi Satija and generic clomid for sale Sriparna Roy in Bengaluru; Editing by Shailesh Kuber and Uttaresh Venkateshwaran)

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