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Equipped with the right applications, a computer can be of great help in virtually any domain of activity. When it comes to designing and precision, no other tool is as accurate as a computer. Moreover, specialized applications such as AutoCAD give you the possibility to design nearly anything ranging from art, to complex mechanical parts or even buildings.
Suitable for business environments and experienced users
After a decent amount of time spent installing the application on your system, you are ready to fire it up. Thanks to the office suite like interface, all of its features are cleverly organized in categories. At a first look, it looks easy enough to use, but the abundance of features it comes equipped with leaves room for second thoughts.
Create 2D and 3D objects
You can make use of basic geometrical shapes to define your objects, as well as draw custom ones. Needless to say that you can take advantage of a multitude of tools that aim to enhance precision. A grid can be enabled so that you can easily snap elements, as well as adding anchor points to fully customize shapes.
With a little imagination and patience on your behalf, nearly anything can be achieved. Available tools allow you to create 3D objects from scratch and have them fully enhanced with high-quality textures. A powerful navigation pane is put at your disposal so that you can carefully position the camera to get a clearer view of the area of interest.
Various export possibilities
Similar to a modern web browser, each project is displayed in its own tab. This comes in handy, especially for comparison views. Moreover, layouts and layers also play important roles, as it makes objects handling a little easier.
Sine the application is not the easiest to carry around, requiring a slightly sophisticated machine to properly run, there are several export options put at your disposal so that the projects itself can be moved around.
Aside from the application specific format, you can save as an image file of multiple types, PDF, FBX and a few more. Additionally, it can be sent via email, directly printed out on a sheet of paper, or even sent to a 3D printing service, if available.
To end with
All in all, AutoCAD remains one of the top applications used by professionals to achieve great precision with projects of nearly any type. It encourages usage with incredible offers for student licenses so you get acquainted with its abundance of features early on. A lot can be said about what it can and can't do, but the true surprise lies in discovering it step-by-step.

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than in the normals for both fMRI and PET, respectively.

Another striking result concerns the relationship between the BOLD signal and the fMRI reference signal. While BOLD signal time courses in patients with PSP-P, CBS, PSP-RS and DLB show similar trends to the time courses of the normalized fMRI reference signal, BOLD signal time courses in patients with PD show clear deviations from fMRI reference signal time courses. This means that in patients with PD we cannot detect the activation pattern expected based on fMRI activation.

Finally, and importantly, we used a visual stimulation paradigm to assess dopamine-related alterations in PSP, CBS, PSP-RS, and DLB patients, while this was not the case for PD patients. However, as we used a strong visual stimulus paradigm, we may not have explored the full extent of the dopamine-related alterations that occur in patients with PSP, CBS, PSP-RS, and DLB.

Conclusions
===========

Our results suggest that PSP, CBS, PSP-RS and DLB are associated with decreased dopamine neurotransmission in the midbrain in PD.

Competing interests
===================

The authors declare that they have no competing interests.

Authors’ contributions
======================

EW designed the study, acquired data, analysed and interpreted the data and drafted the manuscript. MS carried out the voxel-based fMRI analysis, the MRT analysis and the statistical analysis and participated in the interpretation of the data. FH contributed to the interpretation of the data and helped to draft the manuscript. KK contributed to the analysis of the data and was involved in drafting the manuscript. All authors read and approved the final manuscript.

Pre-publication history
=======================

The pre-publication history for this paper can be accessed here:

Acknowledgements
================

We are thankful to the members of the Department of Psychiatry and Psychotherapy for their kind cooperation in participating in this study. This work was supported by the *Etat de Hesse* and the German research foundation (DFG Schwerpunktprogramm SPP 1164, KFO 1127 and NIMH: R01MH086155).
In 3GPP (3rd Generation Partnership Project) LTE (Long Term Evolution), it is under consideration to

What’s New in the AutoCAD?

Create a template that enables users to export shapes for other applications. When you export a drawing to PDF, AutoCAD can export the template, keeping the settings and options from the original file. Save time by having a template to help you automate tasks. (video: 7:10 min.)

Enhance Visual Cues:

Learn to configure color and size scales for specific applications. Create a better overall picture of your work by using these scales. AutoCAD can present information in two ways: numeric scales or a color scale. Both can be displayed on your screen, or they can be stored in templates. Color and numeric scales help you to manage and maintain your designs, especially on color-adjusted displays.

Explore other display features, including transparency, custom symbols, and lines of best fit. You can use transparent symbols to display background colors or digital cameras to show a picture. You can also apply attributes, such as color or a dashed line, to lines of best fit. (video: 6:15 min.)

Project Management:

Explore new or updated features in Project Center. Access more than 30 templates for commonly used software, including Microsoft® Office, Google Earth, AutoCAD, and more. Create your own templates and customize them as needed.

Manage multiple projects from a central location. Each project includes tasks, drawings, versions, and comments from colleagues. You can synchronize drawings from multiple projects, including any changes made to a project’s drawings.

Get organized. Create action plans and manage your projects by using templates. You can create a plan for a project by using a template that includes a list of commonly used steps. You can also create your own step templates and add them to the plan. (video: 1:32 min.)

Explore New Features in Revit:

See and understand your design with 3D views and bills of materials. An interactive graphical user interface (GUI) in 3D views can provide valuable visual information. Create a list of items that a particular component needs. With a bill of materials, you can easily see how your assembly will fit together.

Use Point Cloud technology to create a three-dimensional rendering of a building or other object. You can use this technology to see how the building will look in a room. (video: 4:38 min.)

Automatically convert your drawings into BIM. You can access detailed information in 3D views

System Requirements For AutoCAD:

Windows 7/8/8.1/10 64-bit
Mac OSX 10.8/10.9/10.10/10.11/OSX El Capitan
Browsers:
Internet Explorer 10+
Firefox
Chrome
Opera
Mozilla Firefox requires a 64-bit or compatible browser.
Mac Safari needs to be version 6 or greater, or a 64-bit version of Chrome.
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