In vitro cytotoxicity and pharmacokinetic studies of ketoconazole and ZK 98.299-19C in mice.
The liquid chromatographic (LC) and thin-layer chromatographic (TLC) methods were developed for the estimation of Ketoconazole and ZK 98.299-19C concentrations in plasma or testes tissue of mice. The obtained chromatographic data were utilized to determine pharmacokinetic parameters using the noncompartmental analysis. 179db25a34
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